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These effects are tied to changes in gut-derived hormones, which may further modulate insulin dynamics, satiety, and energy balance

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Consequently, the results of this more conservative analysis were compared with our main results as a sensitivity analysis

Key tips for clinicians include: Ask about gallbladder history before starting therapy Monitor for right upper quadrant pain or nausea after meals Educate patients on when to seek medical evaluation For most, the benefits of GLP1 therapy outweigh the risks, but patient awareness is critical for timely diagnosis and care